BAY-179 是一种有效的、选择性的、物种交叉反应的复合物 I 抑制剂 (IC50=79 μM)。
货号:ajcx26718
CAS:N/A
分子式:C23H21N5OS
分子量：415.5
溶解度:DMF: Slightly soluble,DMSO: Slightly soluble
纯度：98%
存储：Store at -20°C
库存：
现货Background:
BAY-179 is an inhibitor of mitochondrial complex I, also known as NADH dehydrogenase (IC50s = 79, 38, 27, and 47 nM for the human, mouse, rat, and dog enzymes, respectively).1See theStructural Genomics Consortium (SGC)website for more information.
1.Mowat, J., Ehrmann, A.H.M., Christian, S., et al.Identification of the highly active, species cross-reactive complex I inhibitor BAY-179ACS Med. Chem. Lett.13(3)348-357(2022)
