NSC639828 是一种有效的 DNA 聚合酶 α (DNA polymerase α) 抑制剂,IC50 为 70 μM。NSC639828 具有高抗肿瘤活性。NSC639828 具有研究癌症疾病的潜力。
货号:ajcx36970
CAS:134742-26-0
分子式:C18H13BrClN5O3
分子量:462.68
溶解度:DMSO : 100 mg/mL (216.13 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
NSC639828 is a potent inhibitor of DNA polymerase α with an IC50 of 70 μM. NSC639828 has high antitumor activity. NSC639828 has the potential for researching cancer disease[1].
[1]. Abdel-Aziz W, et al. Effect of novel benzoylphenylurea derivatives on DNA polymerase alpha activity using the synthesome-based in vitro model system. Invest New Drugs. 2003;21(4):421-428.