A heterocyclic building block
货号:ajcx21256
CAS:1839-18-5
分子式:C5H4ClN5
分子量：169.6
溶解度:Ethanol: slightly soluble
纯度：98%
存储：Store at -20°C
库存：
现货Background:
2-Chloroadenine is a heterocyclic building block that has been used in the synthesis of adenosine antimetabolites with antineoplastic activity.1It is also the major catabolite of 2-chloro-2'-deoxyadenosine.2
1.Bauta, W.E., Schulmeier, B.E., Burke, B.J., et al.A new process for antineoplastic agent clofarabineOrg. Proc. Res. Dev.8(6)889-896(2004)
2.Bontemps, F., Delacauw, A., Cardoen, S., et al.Metabolism and cytotoxic effects of 2-chloroadenine, the major catabolite of 2-chloro-29-deoxyadenosineBiochem. Pharmacol.59(10)1237-1243(2000)
