Desmethyl ferroquine (SSR97213) 是 Ferroquine 的主要活性代谢产物。Ferroquine 是一种抗疟剂。Desmethyl ferroquine 显著抑制对 Chloroquine 敏感的和耐 Chloroquine 的恶性疟原虫菌株 P. falciparum。
货号:ajcx16508
CAS:903546-18-9
分子式:C22H22ClFeN3
分子量:419.73
溶解度:DMSO: 2.5 mg/mL (5.96 mM); H2O:< 0.1 mg/mL (insoluble)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Desmethyl ferroquine (SSR97213) is the active and major metabolite of Ferroquine. Ferroquine is an antimalarial. Desmethyl ferroquine shows significant activity against Chloroquine-susceptible and resistant P. falciparum strains[1].
[1]. Supan C, et al. Pharmacokinetics of ferroquine, a novel 4-aminoquinoline, in asymptomatic carriers of Plasmodium falciparum infections. Antimicrob Agents Chemother. 2012 Jun;56(6):3165-73.