AER-271

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AER-271

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

规格:	98%
分子量:	463.65

包装与价格：

包装	价格(元)
5mg	询价
10mg	询价
25mg	询价

AER-271 是 AER-270 的膦酸酯前药。AER-271 是一种 aquaporin-4 (AQP4) 抑制剂，有潜力用于急性缺血性中风的研究。
货号:ajcx16838
CAS:634913-39-6
分子式:C15H9ClF6NO5P
分子量：463.65
溶解度:DMSO: 125 mg/mL (269.60 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

AER-271, a phosphonate prodrug derivative of AER-270, is an aquaporin-4 (AQP4) inhibitor for the research of acute ischemic stroke[1].

[1]. Wallisch JS, et al. The aquaporin-4 inhibitor AER-271 blocks acute cerebral edema and improves early outcome in a pediatric model of asphyxial cardiac arrest. Pediatr Res. 2019 Mar;85(4):511-517. [2]. Farr GW, et al. Functionalized Phenylbenzamides Inhibit Aquaporin-4 Reducing Cerebral Edema and Improving Outcome in Two Models of CNS Injury. Neuroscience. 2019 Apr 15;404:484-498.