Buserelin is a synthetic gonadotropin-releasing hormone (GNRH) agonist that is at least 20 times more potent than GNRH.
货号:ajcx18158
CAS:N/A
分子式:C58H83N17O13•XCF3COOH
分子量：1226.4
溶解度:Water: 1 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Buserelin is a synthetic gonadotropin-releasing hormone (GNRH) agonist that is at least 20 times more potent than GNRH. It is a long-acting agent that, after an initial increase in sex hormone levels, decreases the level of circulating gonadotropins and sex hormones. Buserelin (20 µg/kg) reduces tumor growth in a DMBA-induced rat model of mammary cancer. It induces enteric neurodegeneration, decreasing the number of luteinizing hormone receptor-positive neurons in the rat gastrointestinal tract, when administered at a dose of 1 mg/kg for 5 days. Formulations containing buserelin have been used in the treatment of hormone-dependent prostate cancer and endometriosis.