Mephenytoin 是一种抗惊厥药,是 CYP2C19 和 CYP2B6 的底物。
货号:ajcx26804
CAS:50-12-4
分子式:C12H14N2O2
分子量:218.25
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
CYP2C19 and CYP2B6 substrate. Anticonvulsant.
Knabe and Wunn (1980) Racemic and optically active hydantoins from disubstituted cyanoacetic acids. Arch.Pharmacol. 313 53 |Foti et al (2008) CYP2C19 inhibition: the impact of substrate probe selection on in vitro inhibition profiles. Drug Meta. Dispos. 36 523 PMID:18048485 |Tamminga et al (2001) Mephenytoin as a probe for CYP2C19 phenotyping: effect of sample storage, intra-individual reproducibility and occurrence of adverse events. Br.J.Clin.Pharmacol. 51 471 PMID:11422005