MtbHU-IN-1是结合分枝杆菌核型相关蛋白HU(MtbHU)的抑制剂,其对野生型MtbHU蛋白的结合Kd值为98nM.
货号:ajcx12466
CAS:59736-84-4
分子式:C44H36N4O12S2
分子量:876.91
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
MtbHU-IN-1 is an inhibitor of Mycobacterium tuberculosis nucleoid-associated protein HU (MtbHU), with a Kd of 98 nM for binding to WT MtbHU.
MtbHU-IN-1 (SD4) is an inhibitor of Mycobacterium tuberculosis nucleoid-associated protein HU (MtbHU), with Kds of 98 nM, 760 nM, 980 nM, 340 nM and 730 nM for WT and mutant MtbHUs, respectively[1].
[1]. Bhowmick T, et al. Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors. Nat Commun. 2014 Jun 11;5:4124.