(Rac)-LM11A-31 dihydrochloride 是 LM11A-31 dihydrochloride 的异构体。LM11A-31 dihydrochloride 是一种 p75NTR (神经营养蛋白受体 p75) 配体,是有效的 proNGF 拮抗剂。
货号:ajcx15538
CAS:1214672-15-7
分子式:C12H27Cl2N3O2
分子量:316.27
溶解度:H2O: ≥ 200 mg/mL (632.37 mM); Ethanol: 100 mg/mL (316.19 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
(Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride, a p75NTR (neurotrophin receptor p75) Ligand, is a potent proNGF (nerve growth factor) antagonist[1].
[1]. Elshaer SL, et al. Modulation of the p75 neurotrophin receptor using LM11A-31 prevents diabetes-induced retinalvascular permeability in mice via inhibition of inflammation and the RhoA kinase pathway. Diabetologia. 2019 Aug;62(8):1488-1500.