(-)-Rasfonin 是一种真菌次生代谢物,可抑制小 G 蛋白 Ras。 (-)-Rasfonin 在 ACHN 细胞(一种肾癌细胞系)中诱导细胞凋亡、坏死和自噬。
货号:ajcx19124
CAS:303156-68-5
分子式:C25H38O6
分子量:434.6
溶解度:DMSO: 1 mg/ml,Ethanol: Soluble,Methanol: Soluble
纯度:98%
存储:Store at -20°C
库存:
现货Background:
(-)-Rasfonin is a fungal metabolite that has been found in T. terrophilus.1 It inhibits proliferation of mouse splenocytes induced by concanavalin A and LPS (IC50s = 0.7 and 0.5 μg/ml, respectively).
参考文献
1. Fujimoto, H., Okamoto, Y., Sone, E., et al. Eleven new 2-pyrones from a fungi imperfecti, Trichurus terrophilus, found in a screening study guided by immunomodulatory activity. Chem. Pharm. Bull. (Tokyo) 53(8), 923-929 (2005).