A caged neurotransmitter used with photolysis
货号:ajcx22980
CAS:2226362-29-2
分子式:C14H17N3O6.CF3COOH
分子量：437.3
溶解度:Ethanol: 0.25 mg/mL,PBS (pH 7.2): 5 mg/mL
纯度：98%
存储：Store at -20°C
库存：
现货Background:
MNI-caged-L-glutamate is a form of glutamate linked to a 4-methoxy-7-nitroindolinyl (MNI) photoprotecting group that is pharmacologically inactive at neuronal glutamate receptors (up to mM concentrations).1Upon exposure to light (300 - 380 nm excitation), L-glutamate is cleaved of MNI and released within submicroseconds.1This compound can be used to investigate the mechanisms of fast synaptic glutamate receptorsin situ.
1.Canepari, M., Nelson, L., Papageorgiou, G., et al.Photochemical and pharmacological evaluation of 7-nitroindolinyl-and 4-methoxy-7-nitroindolinyl-amino acids as novel, fast caged neurotransmittersJ.Neurosci.Methods112(1)29-42(2001)
