(E)-10-Hydroxynortriptyline(E-10-OH-NT)是Nortriptyline的代谢物。Nortriptyline是三环类抗抑郁药,是Amitriptyline的主要活性代谢物,用于缓解抑郁症状。
货号:ajcx29804
CAS:47132-16-1
分子式:C19H21NO
分子量:279.38
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
(E)-10-Hydroxynortriptyline (E-10-OH-NT) is a metabolite of Nortriptyline . Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].
[1]. Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22(4):371-8.
[2]. Shimoda K, et al. Dean L. Amitriptyline Therapy and CYP2D6 and CYP2C19 Genotype. Biotechnology Information (US); 2012-2017 Mar 23.