Ziresovir (AK0529; RO-0529) 是一种口服有效的,选择性呼吸道合胞病毒 (RSV) 融合 (F) 蛋白 (RSV F) 抑制剂。 Ziresovir 显示抗 RSV 活性 (EC50=3 nM), 并具有药代动力学表现。
货号:ajcx15006
CAS:1422500-60-4
分子式:C22H25N5O3S
分子量:439.53
溶解度:DMSO: 125 mg/mL (284.39 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Ziresovir (AK0529;RO-0529) is a potent, selective, and orally bioavailable respiratory syncytial virus (RSV) fusion (F) protein (RSV F) protein inhibitor. Ziresovir shows anti-RSV activity (EC50=3 nM) and highlights pharmacokinetics in animal species[1].
[1]. Scott SA, et al. Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness. Nat Chem Biol. 2009 Feb;5(2):108-17.