3'-Methoxypuerarin(3'-MOP)是从葛根中提取的异黄酮,具有神经元保护活性。
CAS:117047-07-1
分子式:C22H22O10
分子量:446.4
纯度:98%
存储:Store at -20°C
Background:
3’-Methoxypuerarin (3’-MOP) is an isoflavone extracted from radix puerariae that shows neuron protection activity.
3’-Methoxypuerarin increases the number of surviving neurons in the hippocampal CA1 region and markedly reduces the number of apoptotic pyramidal neurons after ischemia/reperfusion injury. 3’-Methoxypuerarin can protect hippocampal neurons against I/R injury by inhibiting apoptosis[1].
[1]. Liu Y, et al. Protection by 3’-methoxypuerarin of rat hippocampal neurons against ischemia/reperfusion injury. Chin J Physiol. 2010 Apr 30;53(2):136-40.