NVS-CRF38

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NVS-CRF38

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:	1207258-55-6
规格:	98%
分子量:	351.4

包装与价格：

包装	价格(元)
2mg	询价
5mg	询价
10mg	询价
50mg	询价
100mg	询价

NVS-CRF38是一新型CRF1受体拮抗剂，较低的水溶性。
CAS：1207258-55-6
分子式：C19H21N5O2
分子量：351.4
纯度：98%
存储：Store at -20°C

Background:

NVS-CRF38 is a novel corticotropin-releasing factor receptor 1 (CRF1) antagonist with low water solubility.IC50 value: Target: CRF1 antagonist

[1]. Stringer RA, et al. Preclinical metabolism and pharmacokinetics of NVS-CRF38, a potent and orally bioavailable corticotropin-releasing factor receptor 1 antagonist. Xenobiotica. 2014 Apr 3. [2]. Stringer RA, et al. 1-Aminobenzotriazole modulates oral drug pharmacokinetics through cytochrome P450 inhibition and delay of gastric emptying in rats. Drug Metab Dispos. 2014 Jul;42(7):1117-24.