LPA2 receptor non-lipid agonist
CAS：325850-81-5
分子式：C22H17NO4S
分子量：391.44
纯度：98%
存储：Store at -20°C

Background:

Selective lysophosphatidic acid 2 (LPA₂) receptor non-lipid agonist (EC₅₀= 3.3 μM). Does not activate other LPA GPCRs at concentrations up to 10 μM. Antiapoptotic; inhibits activation of caspases 3, 7, 8 and 9, Bax translocation and PARP-1 cleavage. Activates ERK1/2 survival pathway.