Finafloxacin是氟喹诺酮抗微生物剂,在微酸环境中达到最佳功效。
CAS：209342-40-5
分子式：C20H19FN4O4
分子量：398.39
纯度：98%
存储：Store at -20°C

Background:

Finafloxacin is a fluoroquinolone antimicrobial agent that exhibits optimum efficacy in slightly acidic environments. Target: AntibacterialFinafloxacin is a pH-activated fluoroquinolone (belonging to a new 8-cyano subclass) to treat serious bacterial infections associated with an acidic environment, including urinary tract infections (UTIs) and Helicobacter pylori infections. Finafloxacin exhibits optimal efficacy in slightly acidic environments (pH 5.0-6.0), under which other fluoroquinolones lose activity. Finafloxacin is highly selective for bacterial type II topoisomerases, including DNA gyrase and DNA topoisomerase IV. [1]

[1]. McKeage K. Finafloxacin: first global approval. Drugs. 2015 Apr;75(6):687-93.