AdrenocorticotropicHormone(ACTH)(1-10),human是一种促肾上腺皮质激素片段,仅在高浓度(100和1000nM)时才具有弱的α-黑素细胞刺激激素(α-MSH)效力。
CAS:2791-05-1
分子式:C59H78N16O16S
分子量:1299.41
纯度:98%
存储:Store at -20°C
Background:
Adrenocorticotropic Hormone (ACTH) (1-10), human, an adrenocorticotropin hormone fragment, possesses a weak α-melanocyte stimulating hormone (α-MSH) potency only at high doses (100 and 1000 nM).
α-melanocyte stimulating hormone (MSH) induces the differentiation of mouse epidermal melanocytes in vivo and in vitro. Adrenocorticotropic hormone (ACTH) possesses the same amino acid sequence as MSH does[1].
[1]. Hirobe T, et al. ACTH(4-12) is the minimal message sequence required to induce the differentiation of mouse epidermal melanocytes in serum-free primary culture. J Exp Zool. 2000 May 1;286(6):632-40.