Glabranine 是从 Tephrosia s.p 中分离出一种类黄酮,在体外对登革病毒发挥抑制作用。Glabranine 与 DENV 2 型 (DENV2) E 蛋白的可溶性胞外域形成相互作用。
CAS:41983-91-9
分子式:C20H20O4
分子量:324.37
纯度:98%
存储:Store at -20°C
Background:
Glabranine, an flavonoid, is isolated from Tephrosia s.p, exerts a inhibitory effect in vitro on the dengue virus[1].Glabranine forms interaction with the soluble ectodomain of DENV type 2 (DENV2) E protein[2].
[1]. SÁnchez I, et al. Antiviral effect of flavonoids on the dengue virus. Phytother Res. 2000 Mar;14(2):89-92.
[2]. Ismail NA, et al. Molecular Docking and Molecular Dynamics Simulation Studies to Predict Flavonoid Binding on the Surface of DENV2 E Protein. Interdiscip Sci. 2017 Dec;9(4):499-511.