Ceftizoximesodium(SKF-88373)是第三代抗生素,有效抗革兰氏阴性和革兰氏阳性菌,Ceftizoxime结合青霉素结合蛋白(PBPs)和抑制细菌细胞壁的合成。
CAS:68401-82-1
分子式:C13H12N5NaO5S2
分子量:405.38
纯度:98%
存储:Store at -20°C
Background:
Ceftizoxime sodium (SKF-88373) is third generation cephalosporin effective against Gram-negative and Gram-positive bacteria. It binds penicillin-binding proteins (PBPs) and inhibits the bacterial cell wall synthesis.
Ceftizoxime is a third-generation cephalosporin available for parenteral administration. Unlike other third-generation cephalosporins, the whole C-3 side chain in ceftizoxime has been removed to prevent deactivation by hydrolytic enzymes. It rather resembles cefotaxime in its properties, but is not subject to metabolism.