Interiotherin A 是具有从 Kadsura 内部分离的含二苯并环辛二烯骨架的木脂素。 Interiotherin A 抑制 HIV 复制并且表现出抗 HIV 活性,它具有代谢产物和抗 HIV 的作用。
CAS:181701-06-4
分子式:C29H28O8
分子量:504.53
纯度:98%
存储:Store at -20°C
Background:
Interiotherin A is a lignan with a dibenzocyclooctadiene skeleton isolated from Kadsura interior. Interiotherin A inhibits HIV replication to exhibit anti-HIV activity, it has a role as a metabolite and an anti-HIV agent[1].
Interiotherin A (Compounds 1) (0.8-100µg/mL; 4 hours) inhibits HIV replication with EC50 values of 3.1 µg/mL[1]. Cell Cytotoxicity Assay[1] Cell Line: T cell line: HS1
[1]. Chen DF, et al. Two new lignans, interiotherins A and B, as anti-HIV principles from Kadsura interior. J Nat Prod. 1996 Nov;59(11):1066-8.