Alizapride (MS 5080; Litican, Plitican) is a potent dopamine receptor
antagonist with prokinetic and antiemetic effects and can be used for
the theropy of nausea and vomiting. Alizapride demonstrates little
toxicity (particularly after parenteral administration) in mice and
rats. Alizapride is mainly excreted as unmodified drug after oral or
parenteral administration; however, a share of about 25% undergoes
metabolic transformation before deletion. Alizapride (5 mg/kg, s.c.)
antagonizes the decrease in gastrointestinal transit induced by the
above doses of Apomorphine in the rat.
纯度:≥98%
CAS:59338-93-1