c-di-AMP (Cyclic-di-AMP; Cyclic diadenylate) is a potent STING (stimulator of interferon genes) agonist with immunomodulating and ancticancer activities, it binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP (Cyclic diadenylate) is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP (Cyclic diadenylate) acts as a potent mucosal adjuvant stimulating both humorally bioavailable and cellular responses.
纯度:≥98%
CAS:54447-84-6