Cephalothin sodium 是一种头孢类抗生素, 具有广泛的抗菌活性，抑制革兰氏阳性和阴性菌。

Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Cephalothin Sodium is the sodium salt form of cephalothin, a semisynthetic, beta-lactam, the first-generation cephalosporin antibiotic with bactericidal activity. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

58-71-9

C16H15N2NaO6S2

418.41

Cefalotin sodium;Cefalotin;头孢噻吩钠;Cephalothin;Cephalothin sodium

DMSO:23.9 mM
H2O:119.5mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years