VH032-cyclopropane-F 是基于 VH032 的 VHL 配体。它能够利用 linker 与靶蛋白配体连接，得到 PROTAC 分子，如 PROTAC 1。PROTAC 1 是 SMARCA2 和 SMARCA4 的部分降解剂。

VH032-cyclopropane-F is a VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein by a linker to form PROTACs. PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4.

2306193-99-5

C26H33FN4O5S

532.63

E3 ligase Ligand 19;VHL ligand 3;Phenolic VH101;VH032-cyclopropane-F

DMSO:80 mg/mL (150.20 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years