Ospemifene 是非雌激素的选择性雌激素受体调节剂，能够作用于雌激素受体α (Kis:380 nM)和 Erβ (Kis:410 nM)。它可用于研究阴道萎缩乳腺癌。
产品描述
Ospemifene is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. FDA approved on February 26, 2013.
Cas No.
128607-22-7
分子式
C24H23ClO2
分子量
378.9
别名
欧司哌米;奥培米芬;FC-1271a
储存和溶解度
Ethanol:66 mg/mL (174.2 mM)
H2O:<1 mgml
DMSO:70 mg/mL (184.8 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
