Liranaftate 是一种具有抗真菌活性的硫代氨基甲酸酯和角鲨烯环氧酶抑制剂，可研究皮肤癣菌。
产品描述
Liranaftate is a thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in the synthesis of sterol which is essential for cell membrane integrity. By preventing ergosterol synthesis and causing accumulation of squalene, this agent increases cell membrane permeability, cell leakage and eventually cell lysis.
Cas No.
88678-31-3
分子式
C18H20N2O2S
分子量
328.43
别名
利拉萘酯;Piritetrate;M-732
储存和溶解度
DMSO:10mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
