Mocravimod hydrochloride 是 1-磷酸鞘氨醇受体 1 型 (S1PR1) 的有效和口服活性激动剂。
产品描述
Mocravimod hydrochloride is an effecitive and orally active agonist of sphingosine 1-phosphate receptor type 1(S1PR1).
体内活性
In mHC-disparate rat heart allografts, Mocravimod hydrochloride(orally; 0.1 and 1 mg/kg/day; for 100 days) prolongs graft survival and attenuates chronic rejection[1]. Mocravimod hydrochloride ameliorates atherosclerosis in LDL-R(-/-) Mice[2].
Cas No.
509088-69-1
分子式
C24H27Cl2NO3S
分子量
480.45
别名
KRP-203
储存和溶解度
DMSO:95 mg/mL (197.73 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
