产品描述
GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential for asthma and eosinophilic bronchitis treatment.
体外活性
GW 766994 (10 μM) reverses CCL11-induced activation of CDK5, phosphorylations of CDK5, GSK3β, and increased phosphorylation of tau in hippocampal neurons.GW 766994 is a specific chemokine receptor-3 (CCR3) antagonist, which has entered clinical trial for asthma and eosinophilic bronchitis.
Cas No.
408303-43-5
分子式
C21H24Cl2N4O3
分子量
451.35
别名
GW 994
储存和溶解度
DMSO:56 mg/mL (124.07 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
