HERniarin 是一种常见的天然香豆素类化合物，存在于开花植物，具有抗肿瘤的活性。
产品描述
Herniarin is a natural coumarin with antitumor effect.
体外活性
Herniarin is cytotoxic to breast carcinoma cell line MCF-7 (IC50: 207.6 μM). Herniarin (100 μM) also induces apoptosis in MCF-7 cells [1]. Herniarin alone has no obvious cytotoxicity on transitional cell carcinoma (TCC) cells, but when in combination with 5?μg/mL cisplatin, Herniarin (80 μg/mL) potently enhances the antitumor effect of cisplatin and increases chromatin condensation [2].
Cas No.
531-59-9
分子式
C10H8O3
分子量
176.17
别名
7-Methoxycoumarin;Ayapanin;Herniarine;Methyl umbelliferyl ether;7-甲氧基香豆素
储存和溶解度
DMSO:30 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
