AZD9898 是一种白三烯-C4 合成酶抑制剂，IC50 为 0.28 nM。 AZD9898 可用于哮喘研究。 AZD9898 减轻 GABA 结合和肝毒性信号。
产品描述
AZD9898 is an inhibitor of leukotriene-C4 synthetase with an IC50 of 0.28 nM. AZD9898 can be used in studies about asthma. AZD9898 mitigates the GABA binding and hepatic toxicity signal.
体内活性
AZD9898 (10 and 100 mg/kg; oral) is well tolerated and shows no safety concerns[1].
Cas No.
2042347-69-1
分子式
C20H19ClF3N3O4
分子量
457.83
储存和溶解度
DMSO:225mg/mL (491.4mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
