H2L5186303 是一种 LPA2 拮抗剂，可用于哮喘治疗研究。
产品描述
H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.
体外活性
The high cell invasion activity of HT1080-M6 cells is significantly suppressed by H2L5186303[1].
体内活性
H2L5186303 shows strong suppressive efficacy when administered before OVA sensitization and challenge, such as suppression of airway hyper responsiveness, inflammatory cytokine levels, mucin production, and eosinophil numbers[2].
Cas No.
139262-76-3
分子式
C26H20N2O8
分子量
488.45
别名
ZINC33388081
储存和溶解度
DMSO:200 mg/mL (409.5 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
