Thalidomide-O-C8-Boc是一种基于Thalidomide的，可募集CRBN蛋白的Cereblon配体。Thalidomide-O-C8-Boc可通过linker与靶蛋白配体连接，形成PROTAC分子。
| Cas No. | 2225148-52-5 |
| Canonical SMILES | O=C(OC(C)(C)C)CCCCCCCCOC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O |
| 分子式 | C26H34N2O7 |
| 分子量 | 486.56 |
| 储存条件 | -20℃, stored under nitrogen |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Thalidomide-O-C8-Boc is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-Boc can be connected to the ligand for protein by a linker to form PROTACs[1]. [1]. Nathanael S. Gray, et al. Degraders of wee1 kinase. WO2020069105A1. |
