Melanin probe-1 是一种基于 18 F-吡啶酰胺的 PET 探针。Melanin probe-1 可用于恶性黑色素瘤的 PET 显像。Melanin probe-1 具有较高的肿瘤靶向性、良好的肿瘤影像学对比，理想的生物分布模式和体内稳定性好。
| Cas No. | 1420844-62-7 |
| 别名 | N-(2-(二乙基氨基)乙基)-5-氟-2-吡啶甲酰胺 |
| Canonical SMILES | O=C(C1=NC=C(F)C=C1)NCCN(CC)CC |
| 分子式 | C12H18FN3O |
| 分子量 | 239.29 |
| 溶解度 | DMSO: 250 mg/mL (1044.76 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Melanin probe-1 is an 18F-picolinamides based PET probe. Melanin probe-1 can be used for PET imaging of malignant melanoma. Melanin probe-1 exhibits high tumor targeting efficiency, excellent tumor imaging contrasts, desirable biodistribution patterns, and good in vivo stability[1]. [1]. Liu H, et al. Development of 18F-labeled picolinamide probes for PET imaging of malignant melanoma. J Med Chem. 2013;56(3):895‐901. |
