Alkyne-PEG3-NHS 酯是一种不可裂解的 4 单元 PEG 接头,用于抗体-药物偶联 (ADC)。
Cas No. | 1428629-70-2 |
别名 | 丙炔基-三聚乙二醇-丙烯酸琥珀酰亚胺酯 |
分子式 | C16H23NO8 |
分子量 | 357.36 |
溶解度 | good in water, many polar organic solvents |
储存条件 | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Alkyne-PEG3-NHS ester is a bifunctional molecule containing NHS ester and alkyne functional groups. NHS ester group is used for the labeling of amine groups, like lysine and N-terminal NH2, in proteins and peptides. And terminal alkyne group is useful for copper catalyzed Click chemistry (CuAAc) or Sonogashira coupling. PEG3 linker is hydrophilic, and provides a good separation between the parts of the conjugate. |