Thalidomide-5-NH2-CH2-COOH (compound 114) 是一种有效的、选择性的原肌球蛋白受体激酶 (trk) 抑制剂。Thalidomide-5-NH2-CH2-COOH 是 E3 连接酶的配体。Thalidomide-5-NH2-CH2-COOH 具有研究一种或多种疾病的潜力 (信息摘自专利 WO2021170109A1)。
| Cas No. | 2412056-27-8 |
| 分子式 | C15H13N3O6 |
| 分子量 | 331.28 |
| 溶解度 | DMSO : 33.33 mg/mL (100.61 mM; Need ultrasonic) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Thalidomide-5-NH2-CH2-COOH (compound 114) is a potent and selective inhibitor of tropomyosin receptor kinase (trk). Thalidomide-5-NH2-CH2-COOH is a ligand of E3 ligase. Thalidomide-5-NH2-CH2-COOH has the potential for researching one or more diseases (extracted from patent WO2021170109A1)[1]. [1]. Jing Liu, et al. Tropomyosin receptor kinase (trk) degradation compounds and methods of use. Patent WO2021170109A1. |
