CDK1-IN-2是一种CDK1抑制剂，IC50为5.8μM。CDK1-IN-2的激酶谱显示了多种激酶的非选择性抑制。
产品描述
CDK1-IN-2 is a CDK1 inhibitor with IC50 of 5.8 μM. A broad-spectrum kinase profiling of CDK1-IN-2 revealed nonselective inhibition of several kinases.
体外活性
Effect of inhibitors designated CDK1-selective on the cell cycle of HCT-116 cells treated for 24 h, CDK1-IN-2(0-19.8μM) arrested HCT-116 cells in the G2/M phases[1].
Cas No.
220749-41-7
分子式
C17H11ClN2O
分子量
294.73
别名
cdk1 inhibitor 2
储存和溶解度
DMSO:225mg/mL (763.4mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
