UFP-101 是一种有效、选择性和竞争性的NOP受体拮抗剂，pKi为 10.24。UFP-101 对 δ、μ 和 κ 类阿片受体的选择性大于 3000 倍。UFP-101 具有抗抑郁药样作用。
| 生物活性 | UFP-101 is a potent, selective, and competitive antagonist of theNOP receptor, with apKiof 10.24. UFP-101 displays >3000-fold selectivity over δ, μ and κ opioid receptors. UFP-101 shows antidepressant-like effect[1][2]. |
体内研究
(In Vivo) | UFP-101 elicits a pronounced acute and dosedependent antidepressant-like effect in mice submitted to the forced swimming test (FST)[1].
|
| 分子量 | |
| Formula | |
| CAS 号 | |
| Sequence Shortening | |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
