生物活性 | MsbA-IN-6 is a potent inhibitor ofMsbA. MsbA-IN-6 is anantibiotic. Gram-negative ATP-binding cassette (ABC) transporter MsbA, an essential inner membrane protein, transports lipopolysaccharide from the inner leaflet to the periplasmic face of the inner membrane. MsbA-IN-6 killsEscherichia colithrough inhibition of its ATPase and transport activity, with no loss of activity against clinical multidrug-resistant strains[1][2]. |
IC50& Target | MsbA[1] |
分子量 | 451.35 |
Formula | C24H20Cl2N4O |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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