7,8-Didehydrocimigenol

立即咨询

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

150972-72-8

7,8-Didehydrocimigenol 是一种活性三萜，可从升麻 (Cimicifugae rhizoma) 中分离出。7,8-Didehydrocimigenol 抑制 TNF-α 诱导的 VCAM-1 表达，抑制NF-kB活性、ERK1/2 和 Akt 的磷酸化，增加PPAR-γ表达。7,8-Didehydrocimigenol 可用于动脉硬化等心血管疾病的治疗。

生物活性	7,8-Didehydrocimigenol is an active triterpenoid that can be isolated fromCimicifugae rhizoma. 7,8-Didehydrocimigenol inhibits TNF-α-induced VCAM-1 expression, inhibitsNF-kBactivity and phosphorylation of ERK1/2 andAkt, increasesPPAR-γexpression. 7,8-Didehydrocimigenol can be used for the research of cardiovascular disorders such as atherosclerosis^[1].
分子量	486.68
Formula	C₃₀H₄₆O₅
CAS 号	150972-72-8
结构分类	Terpenoids Triterpenes
来源	Plants Ranunculaceae Cimicifuga foetidaLinn.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.