VEGFR-2-IN-18

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VEGFR-2-IN-18

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

VEGFR-2-IN-18 (Compound 15d) 是一种有效的VEGFR-2抑制剂，IC₅₀值为 60 nM。VEGFR-2-IN-18 诱导细胞凋亡 (apoptosis)，具有抗肿瘤活性。

生物活性

VEGFR-2-IN-18 (Compound 15d) is a potentVEGFR-2inhibitor with anIC₅₀of 60 nM. VEGFR-2-IN-18 induces cellapoptosis. VEGFR-2-IN-18 shows antitumor activities^[1].

IC₅₀& Target

VEGFR2

60 nM (IC₅₀)

体外研究
(In Vitro)

VEGFR-2-IN-18 (Compound 15d) shows antiproliferative activities with IC₅₀values of 24.10 ± 2.12, 40.90 ± 3.46, 33.40 ± 2.92 and 221.25 ± 2.55 μM against HepG2, PC3, MCF-7 and WI-38 cells, respectively^[1].

分子量

376.80

Formula

C₂₀H₁₃ClN₄O₂

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.