MAO-B-IN-10

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MAO-B-IN-10

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

MAO-B-IN-10 (compound 4f) 是一种有效的、选择性的、透过血脑屏障的MAO-B(单胺氧化酶-B) 抑制剂，其IC₅₀值为5.3 μM。MAO-B-IN-10 能抑制 (58.2%) 和分解 (43.3%) 自介导的 Aβ 聚集。MAO-B-IN-10 可用于阿尔茨海默病研究。

生物活性

MAO-B-IN-10 (compound 4f) is a potent, selective, BBB-penetratedMAO-B(monoamine oxidase-B) inhibitor, withIC₅₀of 5.3 μM. MAO-B-IN-10 can inhibit (58.2%) and disaggregate (43.3%) self-mediated Aβ (amyloid β) aggregation. MAO-B-IN-10 can be use for Alzheimer’s disease research^[1].

IC₅₀& Target

MAO-B

5.3 ± 0.22 μM (IC₅₀)

MAO-A

15.9 ± 0.1 μM (IC₅₀)

分子量

394.46

Formula

C₂₃H₂₆N₂O₄

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.