MAO A/HDAC-IN-1 是单胺氧化酶 A (MAO A) 和HDAC的双重抑制剂。MAO A/HDAC-IN-1 可用于胶质瘤研究。
生物活性 | MAO A/HDAC-IN-1 is a dual inhibitor ofmonoamine oxidaseA (MAO A)andHDAC. MAO A/HDAC-IN-1 can be used for glioma research[1]. |
IC50& Target[1] | |
体外研究 (In Vitro) | MAO A/HDAC-IN-1 (compound 15) increases histone H3 and α-tubulin acetylation and induce cell death via nonapoptotic mechanisms[1].
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体内研究 (In Vivo) | MAO A/HDAC-IN-1 (compound 15) reduces tumor size, reduced MAO A activity in brain and tumor tissues, and prolonged the survival[1].
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |