8-Hydroxyguanosine是氧化应激的系统标记，也可用作氢氧自由基对RNA损伤的标记。
| Cas No. | 3868-31-3 |
| 别名 | 8-羟基鸟苷 |
| Canonical SMILES | OC[C@@H]1[C@H]([C@H]([C@H](N2C(NC3=C2N=C(N)NC3=O)=O)O1)O)O |
| 分子式 | C10H13N5O6 |
| 分子量 | 299.24 |
| 溶解度 | DMSO: ≥ 250 mg/mL (835.45 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 8-Hydroxyguanosine is a systematic marker of oxidative stress and a marker of hydroxyl radical damage to RNA. [1]. Fiala ES, et al. Oxidative DNA and RNA damage in the livers of Sprague-Dawley rats treated with the hepatocarcinogen 2-nitropropane. Cancer Res. 1989 Oct 15;49(20):5518-22. [2]. Abe T, et al. Remarkable increase in the concentration of 8-hydroxyguanosine in cerebrospinal fluid from patients with Alzheimer's disease. J Neurosci Res. 2002 Nov 1;70(3):447-50. |
