(S)-Bromoenol lactone

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CAS NO:

478288-94-7

(S)-BEL
(S,E)-Bromoenol lactone

(S)-Bromoenol lactone ((S)-BEL) 是一种不可逆的、手性的、基于机制的钙非依赖性磷脂酶A₂β (iPLA₂β) 抑制剂，它抑制大鼠主动脉平滑肌（A10）细胞中血管加压素诱导的花生四烯酸的释放，IC₅₀为 2 μM。

生物活性

(S)-Bromoenol lactone ((S)-BEL) is an irreversible, chiral, mechanism-based inhibitor ofcalcium-independentphospholipase A₂β (iPLA₂β)that inhibits the vasopressin-induced release of arachidonate from cultured rat aortic smooth muscle (A10) cells with anIC₅₀of 2 μM^[1].

IC₅₀& Target

PLA2

分子量

317.18

Formula

C₁₆H₁₃BrO₂

CAS 号

478288-94-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.