SOS1-IN-8 是一种有效的SOS1抑制剂,对 SOS1-G12D 和 SOS1-G12V 的IC50分别为 11.6 和 40.7 nM。
| 生物活性 | SOS1-IN-8 is a potentSOS1inhibitor withIC50s of 11.6 and 40.7 nM for SOS1-G12D and SOS1-G12V, respectively (WO2022017339A1, compound 2)[1]. |
| IC50& Target[1] | SOS1-G12D 11.6 nM (IC50) | SOS1-G12V 40.7 nM (IC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |