KRAS inhibitor-16 (compound 3-11) 是一种有效的KRAS G12C抑制剂，IC50为 0.457 μM。KRAS inhibitor-16 在 MIA PaCA-2，A549 细胞中显示出 p-ERK 抑制活性，IC50s 分别为 3.06，11.1 μM。 KRAS inhibitor-16 具有研究胰腺癌，结直肠癌和肺癌的潜力。
| 生物活性 | KRAS inhibitor-16 (compound 3-11) is a potentKRAS G12Cinhibitor with anIC50of 0.457 μM. KRAS inhibitor-16 shows p-ERK inhibition activities with IC50s of 3.06, 11.1 μM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-16 has the potential for the research of pancreatic, colorectal, and lung cancers[1]. |
| IC50& Target | |
| 分子量 | |
| Formula | |
| CAS 号 | |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
