Dyphylline (Diprophylline) 是一种有效的 A1/A2 腺苷受体拮抗剂和环核苷酸磷酸二酯酶抑制剂。
| Cas No. | 479-18-5 |
| 别名 | 二羟丙茶碱; Diprophylline |
| 化学名 | 7-(2,3-dihydroxypropyl)-1,3-dimethylpurine-2,6-dione |
| Canonical SMILES | CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(CO)O |
| 分子式 | C10H14N4O4 |
| 分子量 | 254.24 |
| 溶解度 | ≥ 7.8 mg/mL in DMSO, ≥ 21.96 mg/mL in EtOH with ultrasonic and warming, ≥ 17.17 mg/mL in Water |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Dyphylline acts as an adenosine receptor antagonist and phosphodiesterase inhibitor, which is used in the treatment of respiratory disorders.Target: Adenosine Receptor; PDEDyphylline (trade names Dilor, Lufyllin), also known as diprophylline, is a xanthine derivative with bronchodilator and vasodilator effects. It is used in the treatment of respiratory disorders like asthma, cardiac dyspnea, and bronchitis. It acts as an adenosine receptor antagonist and phosphodiesterase inhibitor. References:
[1]. Schwabe U, et al. Xanthine derivatives as antagonists at A1 and A2 adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol. 1985 Sep;330(3):212-21.
[2]. Iancu L, et al. Trials with xanthine derivatives in systemic treatment of psoriasis. Dermatologica. 1979;159(1):55-61. |
