Pitofenone (hydrochloride) 是一种解痉化合物，可抑制牛红细胞和电鳗的乙酰胆碱酯酶 (AChE) 活性，Kis 分别为 36 和 45 μM。
| Cas No. | 1248-42-6 |
| 别名 | 吡托非农盐酸盐 |
| 化学名 | 2-[4-[2-(1-piperidinyl)ethoxy]benzoyl]-benzoic acid, methyl ester, monohydrochloride |
| Canonical SMILES | O=C(C1=CC=CC=C1C(OC)=O)C(C=C2)=CC=C2OCCN3CCCCC3.Cl |
| 分子式 | C22H25NO4.HCl |
| 分子量 | 403.9 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 25 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS(pH 7.2) (1:5): 0.16 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Pitofenone is an antispasmodic agent and an inhibitor of acetylcholinesterase (AChE; Kis = 36 and 45 μM for bovine erythrocyte and electric eel enzyme, respectively). It inhibits acetylcholine-induced contractions of isolated guinea pig ileum when used at a concentration of 2.5 μM. |
