Leucomethylene blue (TRx0237) mesylate 是一种具有口服活性的第二代 tau 蛋白聚集抑制剂（Ki 为 0.12 μM），可用于阿尔茨海默病的研究。
| Cas No. | 1236208-20-0 |
| 别名 | TRx0237 mesylate; Methylene blue leuco base mesylate |
| Canonical SMILES | CN(C)C1=CC(SC2=CC(N(C)C)=CC=C2N3)=C3C=C1.CS(=O)(O)=O.CS(=O)(O)=O |
| 分子式 | C18H27N3O6S3 |
| 分子量 | 477.62 |
| 溶解度 | Water : ≥ 31 mg/mL (64.91 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Leucomethylene blue (Mesylate) is a common reduced form of Methylene Blue, Methylene Blue is a member of the thiazine class of dyes. Target:Methylene blue has long been used as an antiseptic and therapeutic agent with both human and veterinary applications. References:
[1]. Gaudette NF, et al. Determination of methylene blue and leucomethylene blue in male and female Fischer 344 rat urine andB6C3F1 mouse urine. J Anal Toxicol. 2005 Jan-Feb;29(1):28-33. |
